Abstract
WHEN humans reach a high altitude there is a marked reduction in the rate of urinary excretion of aldosterone with a slow return to normal1. These changes account for the parallel decrease and increase in rates of salivary and urinary excretion of potassium and sodium respectively. A difference of about a factor of three in the ratio of salivary sodium to potassium has been observed for an altitude as low as 2,400–3,000 m compared with values near sea level. Because of the marked chemical similarity between potassium and caesium, a transitory change in the rate of excretion of caesium might be expected to accompany a change in altitude, and we have observed such an effect in a volunteer who was on an exchange visit from Harwell (altitude 100 m) to Los Alamos (altitude 2,200 m).
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References
Ayres, P. J., Hurter, R. C., Williams, E. S., and Rundo, J., Nature, 191, 78 (1961).
Rundo, J., Brit. J. Radiol., 37, 108 (1964); Boni, A. L., Nature, 222, 1188 (1969).
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RUNDO, J., RICHMOND, C. Altitude Effect on the Biological Half Life of Caesium in Man. Nature 225, 83–84 (1970). https://doi.org/10.1038/225083a0
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DOI: https://doi.org/10.1038/225083a0
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