Abstract
Crystals containing multiple species of tRNA give single crystal X-ray diffraction patterns with a minimum spacing of 3 Å. These crystals display a simplicity of lattice symmetry and unit cell dimensions that makes them particularly suitable for structure analysis to near atomic resolution. The finding of such crystals confirms the marked similarity of tRNAs at the level of tertiary structure.
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References
Madison, J. T., Ann. Rev. Biochem., 37, 131 (1968).
Fresco, J. R., Adams, A., Ascione, R., Henley, D., and Lindahl, T., Cold Spring Harbor Symp. Quant. Biol., 31, 527 (1966).
Sueoka, N., Kano-Sueoka, T., and Gartland, W. J., Cold Spring Harbor Symp. Quant. Biol., 31, 571 (1966).
Holley, R. W., Apgar, J., Everett, G. A., Madison, J. T., Marquisee, M., Merril, S. H., Penswick, J. R., and Zamir, A., Science, 147, 1462 (1965).
Zachau, H. G., Dutting, D., Feldmann, H., Melchers, F., and Karau, W., Cold Spring Harbor Symp. Quant. Biol., 31, 417 (1966).
Fresco, J. R., Blake, R. D., and Langridge, R., Nature, 220, 5174 (1968).
Blake, R. D., Fresco, J. R., and Langridge, R., Fed. Proc., 28, 409 (1969).
Blake, R. D., Langridge, R., and Fresco, J. R., Acta Cryst., Congress Abstracts, A 25, S177 (1969).
Lindahl, T., and Fresco, J. R., in Methods in Enzymology: Nucleic Acids (edit. by Grossman, L., and Moldave, K.), 12, A, 601 (Academic Press, New York, 1967).
Lindahl, T., Henley, D. D., and Fresco, J. R., J. Amer. Chem. Soc., 87, 4961 (1965).
Henley, D. D., Lindahl, T., and Fresco, J. R., Proc. US Nat. Acad. Sci., 55, 191 (1966).
Lindahl, T., Adams, A., and Fresco, J. R., Proc. US Nat. Acad. Sci., 55, 941 (1966).
Clark, B. F., Doctor, B. P., Holmes, K. C., Klug, A., Marcker, K. A., Morris, S. J., and Paradies, H. H., Nature, 219, 1222 (1968).
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BLAKE, R., FRESCO, J. & LANGRIDGE, R. High-resolution X-ray Diffraction by Single Crystals of Mixtures of Transfer Ribonucleic Acids. Nature 225, 32–35 (1970). https://doi.org/10.1038/225032a0
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DOI: https://doi.org/10.1038/225032a0
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