Abstract
Eukaryotic cells contain a special class of cytoplasmic particles, I-somes, which contain DNA. This informational DNA may act as an intermediary carrying genetic information from the nucleus to the cytoplasm where it is transcribed and translated. The key events in differentiation may not be regulation of mRNA transcription but regulation of the production of I-DNA and I-somes.
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BELL, E. I-DNA: Its Packaging into I-somes and its Relation to Protein Synthesis during Differentiation. Nature 224, 326–328 (1969). https://doi.org/10.1038/224326a0
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DOI: https://doi.org/10.1038/224326a0
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