Abstract
THERE is uncertainty about the chemical nature of spermagglutinins detected in the sera of some men and some women. The investigations described in this article gave results which appear to conflict with earlier suggestions that they are antibodies1 or γ-globulins2 and, in particular, IgG3. Preliminary studies in this laboratory, using ammonium sulphate fractionation of several spermagglutinating sera, had shown that the 60 per cent saturated fractions possessed the greatest spermagglutinating activity, whereas the greatest concentrations of γ-globulins were in the 40 per cent fractions4.
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References
Franklin, R. R., and Dukes, C. D., Amer. J. Obstet. Gynec., 89, 6 (1964).
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Boettcher, B., and Hay, J., Proceedings of the Symposium on the Immunology of Spermatozoa and Fertilization (Varna, Bulgaria, 1967, in the press).
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Osterland, C. K., in Methods in Immunology and Immunochemistry (edit. by Williams, C. A. and Chase, M. W.), 2, (Academic Press, New York, 1968).
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BOETTCHER, B., KAY, D. Fractionation of a Human Spermagglutinating Serum. Nature 223, 737–738 (1969). https://doi.org/10.1038/223737a0
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DOI: https://doi.org/10.1038/223737a0
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