Abstract
WE have found significantly higher titres of antistreptolysin O (ASO) in fifty mothers of G1-trisomic children than in fifty age-matched mothers who had borne no children known to be affected with chromosomal aneuploidy. These observations suggest that the mothers of G1-trisomics may be characterized by detectable immunological differences.
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References
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ZSAKO, S., KAPLAN, A. Titres of Antistreptolysin O in Mothers of Children affected with Down's Syndrome. Nature 223, 1281–1282 (1969). https://doi.org/10.1038/2231281a0
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DOI: https://doi.org/10.1038/2231281a0
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