Abstract
KNOWLEDGE of the chemistry of the ABO blood-group antigens is based principally on investigations of water-soluble blood-group substances of glycoprotein nature, occurring in body secretions. The serological determinants in blood-group A, B and H active glycoproteins have been found to be α-N-acetyl-D-galactosamine, α-D-galactose and α-L-fucose residues, respectively1. There is good evidence, however, that the blood-group antigens of erythrocytes, in contrast to the water soluble substances, are glycolipids. Their detailed structure has not yet been established2.
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SCHENKEL-BRUNNER, H., TUPPY, H. Enzymatic Conversion of Human O into A Erythrocytes and of B into AB Erythrocytes. Nature 223, 1272–1273 (1969). https://doi.org/10.1038/2231272a0
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DOI: https://doi.org/10.1038/2231272a0
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