Abstract
THE size or extent of a liver resection influences (a) the rate of liver regrowth grossly, that is to say, the larger the resection, the more rapid the regrowth1,2; (b) the mitotic index in the remnant liver, which increases with more extensive resection3,4; and (c) the uptake of labelled DNA precursors by the remnant liver, which is increased with larger resections5. We have studied the effect of a large versus a small hepatic resection on the characteristics of the tissue culture of the remnant (unremoved) liver tissue, at varying intervals after partial hepatectomy.
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HAYS, D., TEDO, I., OKUMURA, S. et al. Hepatic Regeneration: Effect of Size of Resection on in vitro Growth of Remnant Liver Cells. Nature 220, 286–287 (1968). https://doi.org/10.1038/220286a0
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DOI: https://doi.org/10.1038/220286a0
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