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Reversion of Properties in Cells transformed by Polyoma Virus

Nature volume 220, pages 1203–1206 (1968)Cite this article

Abstract

Clones of polyoma virus transformed cells in which the transformed state has become a hereditary cellular property can produce a high frequency of variants with a reversion of properties characteristic of transformation. This reversion is not associated with a loss of the virus genome.

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References

  1. Stoker, M., Nature, 218, 234 (1968).

    Article  ADS  CAS  Google Scholar 

  2. Winocour, E., and Sachs, L., Virology, 8, 397 (1959).

    Article  CAS  Google Scholar 

  3. Macpherson, I., and Montagnier, L., Virology, 23, 291 (1964).

    Article  CAS  Google Scholar 

  4. Stoker, M., J. Cell Sci., 2, 293 (1967).

    CAS  Google Scholar 

  5. Borek, C., and Sachs, L., Proc. US Nat. Acad. Sci., 56, 1705 (1966).

    Article  ADS  CAS  Google Scholar 

  6. Habel, K., Virology, 25, 55 (1965).

    Article  CAS  Google Scholar 

  7. Fogel, M., and Defendi, V., Proc. US Nat. Acad. Sci., 58, 967 (1967).

    Article  ADS  CAS  Google Scholar 

  8. Aloni, Y., Winocour, E., and Sachs, L., J. Mol. Biol., 31, 415 (1968).

    Article  CAS  Google Scholar 

  9. Huberman, E., and Sachs, L., J. Nat. Cancer Inst., 40, 329 (1968).

    CAS  PubMed  Google Scholar 

  10. Ossovski, L., and Sachs, L., Proc. US Nat. Acad. Sci., 58, 1938 (1967).

    Article  ADS  CAS  Google Scholar 

  11. Pollack, R. E., Green, H., and Todaro, G. J., Proc. US Nat. Acad. Sci., 60, 126 (1968).

    Article  ADS  CAS  Google Scholar 

  12. Marin, G., and Littlefield, J. W., J. Virol., 2, 69 (1968).

    CAS  PubMed  PubMed Central  Google Scholar 

  13. Macpherson, I., Recent Results Cancer Res., 6, 1 (1966).

    Google Scholar 

  14. Weiss, M. C., Ephrussi, B., and Scaletta, L. J., Proc. US Nat. Acad. Sci., 59, 1132 (1968).

    Article  ADS  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Genetics, Weizmann Institute of Science, Rehovot, Israel

    ZELIG RABINOWITZ & LEO SACHS

Authors
  1. ZELIG RABINOWITZ
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  2. LEO SACHS
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RABINOWITZ, Z., SACHS, L. Reversion of Properties in Cells transformed by Polyoma Virus. Nature 220, 1203–1206 (1968). https://doi.org/10.1038/2201203a0

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