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Effect of Post-coital Unilateral Ovariectomy on Implantation in Mice

Abstract

UTERO-OVARIAN relationships have been studied extensively1–3. While there is reliable evidence for a local influence on the ovary by the uterine horn of the same side4,5, evidence for the reciprocal effect—that of the ovary on the ipsilateral uterine horn—is much less convincing. At the request of Professor Melampy of the University of Iowa, experiments were undertaken in Cambridge to see if such an effect could be demonstrated in mice by means of unilateral ovariectomy performed at varying times after coitus. Similar experiments were carried out independently at the Royal Veterinary College in London, and because the findings are very alike it was decided to report them jointly.

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References

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  2. Bland, K. P., and Donovan, B. T., in Advances in Reproductive Physiology (edit. by McLaren, A.), 1, 179 (Logos and Academic Press, London, 1966).

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  3. Psychoyos, A., in Advances in Reproductive Physiology (edit. by McLaren, A.), 2, 257 (Logos and Academic Press, London, 1967).

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BRUCE, H., RENWICK, A. & FINN, C. Effect of Post-coital Unilateral Ovariectomy on Implantation in Mice. Nature 219, 733–734 (1968). https://doi.org/10.1038/219733a0

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  • DOI: https://doi.org/10.1038/219733a0

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