Abstract
I HAVE proposed a comprehensive theory of cerebral amine function which links biochemical, physiological, psychological and clinical phenomena1,2. One hypothesis derived from this general theory is that methysergide should benefit patients with mania. The results of trials in the first five patients are sufficiently notable for a preliminary account to be given.
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References
Dewhurst, W. G., J. Psychosom. Res., 9, 115 (1965).
Dewhurst, W. G., Nature, 218, 1130 (1968).
Kraepelin, E., Psychiatrie, 1237 (J. A. Barth, Leipzig, 1913).
Mayer-Gross, W., Slater, E., and Roth, M., Textbook of Psychiatry, second ed., 211 (Cassell, London, 1960).
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DEWHURST, W. Methysergide in Mania. Nature 219, 506–507 (1968). https://doi.org/10.1038/219506b0
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DOI: https://doi.org/10.1038/219506b0
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