Abstract
CURRENT knowledge suggests that the bacterial chromosome is specifically attached to the cell membrane, and that this attachment is required for DNA replication1–7. Replication of φX 174 bacteriophage DNA may also require a specific site on the bacterial membrane8–13. From the idea of a specific membrane attachment site required for DNA replication, a molecular model can be developed which may help to explain several poorly understood aspects of the control of DNA replication. The model is simple and is consistent with current ideas, but apparently has not been discussed before. We will hereafter use the word “site” to refer to the non-DNA material (presumably a complex of enzymes and structural proteins) which distinguishes between membrane at the point of DNA attachment and other membrane.
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MARVIN, D. Control of DNA Replication by Membrane. Nature 219, 485–486 (1968). https://doi.org/10.1038/219485a0
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DOI: https://doi.org/10.1038/219485a0
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