Abstract
THERE is evidence that in the small intestine and colon of mammals the transport of Cl ions and of HCO3 is, to a certain extent, interdependent. Thus the movement of bicarbonate ions across the small intestine shows some dependence on the presence of Cl ions in the lumen, and it has been suggested that some Cl ions are absorbed in exchange for bicarbonate ions secreted into the lumen of the small intestine and colon1–4. Because a relationship may exist therefore between CO2 metabolism and ion transport in the intestine, the question of the presence of the enzyme carbonic arihydrase (E.G.4.2.1.1) in the intestinal tract is important.
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CARTER, M., PARSONS, D. Carbonic Anhydrase Activity of Mucosa of Small Intestine and Colon. Nature 219, 176–177 (1968). https://doi.org/10.1038/219176a0
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DOI: https://doi.org/10.1038/219176a0
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