Abstract
VARIOUS observations1–4 seemed to support the concept of stability of DNA while others contradicted it. The experiments, using autoradiography and counting techniques, showed in some cells incorporation of precursors in excess of requirements for cell-division or permanent polyploidy5–8,10–12, significant differences in the DNA content of cells depending on the functional state (reviewed in ref. 9), and the appearance and disappearance of transient DNA13,14.
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PELC, S. Turnover of DNA and Function. Nature 219, 162–163 (1968). https://doi.org/10.1038/219162a0
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DOI: https://doi.org/10.1038/219162a0
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