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Chromosome Replication and Cell Division in Escherichia coli 15T after Growth in the Absence of DNA Synthesis

Abstract

THIS communication is concerned with the recommencement of chromosome replication and cell division of E. coli after growth in the absence of DNA synthesis. When DNA synthesis is allowed to resume, cells first synthesize an amount of DNA appropriate to their masses, and only then recover their ability to divide and give rise to fully viable progeny. This result indicates that the ratio of DNA/mass is a factor in the control of cell division.

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DONACHIE, W., HOBBS, D. & MASTERS, M. Chromosome Replication and Cell Division in Escherichia coli 15T after Growth in the Absence of DNA Synthesis. Nature 219, 1079–1080 (1968). https://doi.org/10.1038/2191079a0

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