Abstract
The role of phytohaemagglutinin (PHA) determinants and lymphocyte surface reactive sites has been investigated in the lymphocyte transformation phenomenon. Results suggest that the mitogenic moiety of the PHA molecule is closely related to or identical with the antigenic determinant sites, and that some of these PHA antigenic sites are similar to those found amongst the antigenic configuration on the surface of lymphocytes.
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SIMONS, M., FOWLER, R. & FITZGERALD, M. Mechanism of Lymphocyte Transformation induced by Phytohaemagglutinin. Nature 219, 1021–1025 (1968). https://doi.org/10.1038/2191021a0
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DOI: https://doi.org/10.1038/2191021a0
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