Abstract
IN 1966 New1 described a technique for growing the rat foetus in vitro and pointed out the advantages of homologous serum as a culture medium. I have compared the growth and development of the rat foetus in vivo and in vitro in order to assess the suitability of this animal for experiments in teratogenesis. If good growth and differentiation of normal embryos occur in vitro, then a simple experimental system exists in which the effects of various teratogens can be examined.
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References
New, D. A. T., J. Reprod. Fertil., 12, 509 (1966).
Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., J. Biol. Chem., 193, 265 (1951).
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BERRY, C. Comparison of in vivo and in vitro Growth of the Rat Foetus. Nature 219, 92–93 (1968). https://doi.org/10.1038/219092a0
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DOI: https://doi.org/10.1038/219092a0
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