Abstract
SPECULATION about alveolar size usually centres on the provision of a diffusing surface area adequate for metabolic needs. Tenney and Remmers1, from a survey of lungs in mammals of many different sizes from the bat upwards, concluded that where m = body mass. The resting metabolic rate is proportional to m0.74 when animals such as the dugong and manatee which have a sluggish metabolism are excluded2. We deduce that which indicates that variation of alveolar diameter with body mass for the appropriate animals is gradual. This is supported by data which were collected to determine directly the relationship between alveolar size and body mass.
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References
Tenney, S. M., and Remmers, J. E., Nature, 197, 54 (1963).
Brody, S., Bioenergetics and Growth (Rheinhold, New York, 1945).
Rashevsky, N., Bull. Math. Biophys., 24, 229 (1962).
Rashevsky, N., Mathematical Biophysics: Physico-Mathematical Foundations of Biology, third ed., 2 (Dover Publications Inc., New York, 1960).
Comroe, J. H., Foster, R. E., DuBois, A. B., Briscoe, W. A., and Carlsen, E., The Lung, second ed., 133 (Year Book Medical Publishers Inc. Chicago, 1962).
Weibel, E. R., Morphometry of the Human Lung, 42, 60 and 66–7 (Springer-Verlag, Berlin, 1963).
Carslaw, H. S., and Jaeger, J. C., Conduction of Heat in Solids, second ed., 237 (The Clarendon Press, Oxford, 1959).
Dittmer, D. S., and Grebe, R. M., Handbook of Respiration, Table 41 (Saunders and Co., Philadelphia and London, 1958).
Cumming, G., Crank, J., Horsfield, K., and Parker, I., Resp. Physiol., 1, 58 (1966).
Pattle, R. E., Proc. Roy. Soc., B, 148, 217 (1958).
Tierney, D. F., and Johnson, R. P., J. Appl. Physiol., 20, 1253 (1965).
Tenney, S. M., and Remmers, J. E., J. Appl. Physiol., 21, 1328 (1966).
Storey, W. E., and Staub, N. C., J. Appl. Physiol., 17, 391 (1962).
Macklin, C. C., and Hartroft, W. S., Extramural Rep. Canad. Subcommittee on Physiological Aspects of Chemical Warfare, C.P. 35 (June 30, 1943).
Tenney, S. M., and Bartlett, D., Resp. Physiol., 3, 130 (1967).
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SPELLS, K. Some Physical Considerations relevant to the Dimensions of Lung Alveoli. Nature 219, 64–66 (1968). https://doi.org/10.1038/219064a0
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DOI: https://doi.org/10.1038/219064a0
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