Abstract
Treatment of Moloney induced tumour cells with heparin and other acid mucopolysaccharides blocks cell surface antigens thereby altering transplantation behaviour and cytotoxicity reactions.
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Change history
01 July 1968
In the article "Transplantation and Cyto-toxicity Changes induced by Acid Mucopolysaccharides" by Muriel Lippman (Nature, 219, 33; 1968) the beginning of the second paragraph should read: "Both the histo-chemical observation that applied AMPS can coat cell surfaces3,4 and the increased electrophoretic mobility produced in a variety of ascites tumour cells after exposure to the sodium salt of heparin1 suggest that surface coating can explain the experimental observations".
References
Lippman, M., in Proc. Symp. Epithelial Mesenchymal Interactions (edit. by Fleischmajer, R., and Billingham, R.) (Williams and Wilkins, Baltimore, in the press).
Lippman, M., Trans. NY Acad. Sci., 27, 342 (1965).
Mayhew, E., and Roe, E., Brit. J. Cancer, 18, 537 (1964).
Gasic, G., and Baydak, T., in Intern. Symp. Biol. Interactions in Normal and Neoplastic Growth (edit. by Brennen, M., and Simpson, W.) (Little, Brown and Co., Boston, 1961).
Ceppellini, R., and Landy, M., J. Exp. Med., 117, 321 (1963).
Sanford, B. H., Transplantation, 5, 1273 (1967).
Mayhew, E., and Roe, E., Brit. J. Cancer, 18, 528 (1964).
Klein, G., and Klein, E., J. Nat. Cancer Inst., 32, 547 (1964).
Moller, G., J. Exp. Med., 114, 415 (1961).
Taylor, H. E., and Culling, C. F. A., Lab. Invest., 15, 1960 (1966).
Currie, G. A., Nature, 215, 164 (1967).
Haughton, G., Haot, J., Revesz, L., and Klein, G., Science, 150, 769 (1965).
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LIPPMAN, M. Transplantation and Cytotoxicity Changes induced by Acid Mucopolysaccharides. Nature 219, 33–36 (1968). https://doi.org/10.1038/219033a0
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DOI: https://doi.org/10.1038/219033a0
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