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Effects of Catecholamines on Rat Mesentery Mast Cells

Abstract

THERE have been reports of results which suggest in vivo or in vitro release of histamine caused by adrenaline or noradrenaline in the rat1,2 and other species3–5, but these reports are not wholly accepted as conclusive evidence6,7. As well as amine release, degranulation of mast cells is one of the activities of most histamine releasers active on rat tissues. This communication presents the results of a study of the effects of catecholamines on the morphology of the rat mesentery mast cells, undertaken to provide further information about the effect of catecholamines on a histamine storage site in the mesentery.

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DE OLIVEIRA, M., ROTHSCHILD, A. Effects of Catecholamines on Rat Mesentery Mast Cells. Nature 218, 382–384 (1968). https://doi.org/10.1038/218382a0

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