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Immunochemical Difference between Iron-saturated and Unsaturated Human Transferrin

Nature volume 218, pages 375–377 (1968)Cite this article

Abstract

BINDING of metal ions to metalloproteins is known to induce changes in the physical and chemical properties of the apoproteins1–5. Metal binding may also modify the immunological behaviour of the protein, and recently a decreased antigenicity of metal–conalbumin complexes has been shown using the light-scattering method6. It is not known, however, whether such quantitative modifications involve part or all of the molecule's antigenic sites.

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Authors and Affiliations

  1. Institut de Recherches sur les Maladies du Sang, Hôpital Saint Louis, 75 Paris 100, France

    F. M. KOURILSKY

  2. Institut de Recherches sur le Cancer (CNRS), 94, Villejuif, France

    P. BURTIN

Authors
  1. F. M. KOURILSKY
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  2. P. BURTIN
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KOURILSKY, F., BURTIN, P. Immunochemical Difference between Iron-saturated and Unsaturated Human Transferrin. Nature 218, 375–377 (1968). https://doi.org/10.1038/218375a0

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