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Genetically Controlled Cross Resistance to Polyene Antibiotics in Saccharomyces cerevisiae

Nature volume 218, pages 369–370 (1968)Cite this article

Abstract

POLYENE resistant strains of fungi have been reported by several workers. In several instances these strains have been tested for cross resistance to other polyenes1–3: strains of Candida albicans isolated as resistant to candidin were also resistant to amphotericin B and vice versa1, but neither type was resistant to nystatin. Cross resistance was found to amphotericin B and nystatin in one strain of Candida tropicalis but not in isolates of five other Candida species resistant to one or other of these two antibiotics2. In contrast, a nystatin-resistant isolate of Candida stellatoidea was also resistant to amphotericin A, amphotericin B, endomycin, filipin and pimaricin3.

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References

  1. Hebeka, E. K., and Solotorovsky, M., J. Bact., 89, 1533 (1965).

    CAS  PubMed  Google Scholar 

  2. Littman, M. L., Pisano, M. A., and Lancaster, R. M., Antibiotics Ann., 981 (1958).

  3. Bradley, G. S., Farber, P. J., and Jones, L. A., Antimicrobial Agents Ann., 558 (1960).

  4. Ahmed, K. A., and Woods, R. A., Genet. Res., Camb., 9, 179 (1967).

    Article  CAS  Google Scholar 

  5. Ahmed, K. A., thesis, Univ. Sheffield (1967).

  6. Bergy, M. E., and Eble, T. E., Biochemistry, 7, 653 (1968).

    Article  CAS  Google Scholar 

  7. Lampen, J. O., Symp. Soc. Gen. Microbiol., 16, 111 (1966).

    CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Genetics, University of Sheffield,

    R. A. WOODS & K. A. AHMED

  2. Department of Genetics, Faculty of Agriculture, University of Cairo,

    R. A. WOODS

Authors
  1. R. A. WOODS
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  2. K. A. AHMED
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WOODS, R., AHMED, K. Genetically Controlled Cross Resistance to Polyene Antibiotics in Saccharomyces cerevisiae. Nature 218, 369–370 (1968). https://doi.org/10.1038/218369a0

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  • DOI: https://doi.org/10.1038/218369a0

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