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Prostaglandins released by the Spleen

Nature volume 218, pages 1135–1140 (1968)Cite this article

Abstract

Experiments with dogs have shown that both prostaglandin E2 and F2α are released when the spleen is contracted by nerve stimulation or by adrenaline. The prostaglandins are not released from the nerves, but derive from smooth muscle cells or other cells with similar adrenergic innervation. The prostaglandin release is not the cause of splenic contraction.

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Authors and Affiliations

  1. Departments of Pharmacology and Biochemistry, Institute of Basic Medical Sciences, Royal College of Surgeons of England,

    N. GILMORE, J. R. VANE & J. H. WYLLIE

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  1. N. GILMORE
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  2. J. R. VANE
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  3. J. H. WYLLIE
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GILMORE, N., VANE, J. & WYLLIE, J. Prostaglandins released by the Spleen. Nature 218, 1135–1140 (1968). https://doi.org/10.1038/2181135a0

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