Abstract
THERE have been conflicting reports about the actions of strychnine on cortical inhibitions. Inhibition of cortical neurones by direct cortical stimulation is resistant to strychnine1,2. The “recurrent” inhibition of cortical neurones during stimulation of the pyramidal tract has been said to be both resistant to strychnine1,3 and antagonized by strychnine4–7.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Crawford, J. M., Curtis, D. R., Voorhoeve, P. E., and Wilson, V. J., Nature, 200, 845 (1963).
Krnjević, K., Randić, M., and Straughan, D. W., J. Physiol., 184, 78 (1966).
Brooks, V. B., and Asanuma, H., Amer. J. Physiol., 208, 674 (1965).
Susuki, H., and Tukahara, Y., Jap. J. Physiol., 13, 386 (1963).
Pollen, D. A., and Ajmone Marsan, C., J. Neurophysiol., 28, 342 (1965).
Stefanis, C., and Jasper, H., Intern. J. Neuropharmacol., 4, 125 (1965).
Sawa, M., Maruyama, N., Kaji, S., and Nakamura, K., Jap. J. Physiol., 16, 126 (1966).
Krnjević, K., and Phillis, J. W., Brit. J. Pharmacol. Chemother., 20, 471 (1963).
Krnjević, K., Siminoff, R., and Straughan, D. W., Exp. Neurol., 9, 236 (1964).
Phillis, J. W., and York, D. H., Brain Res., 5, 517 (1967).
Moore, R. Y., Shiu-Loong Wong, R., and Heller, A., Arch. Neurol., 13, 346 (1965).
Heller, A., Seiden, L. S., and Moore, R. Y., Intern. J. Neuropharmacol., 5, 91 (1966).
Andén, N. E., Dahlström, S., Fuxe, K., Larsson, K., Olson, L., and Ungerstedt, U., Acta Physiol. Scand., 67, 313 (1966).
Biscoe, T. J., and Curtis, D. R., Science, 151, 1230 (1965).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
PHILLIS, J., YORK, D. Strychnine Block of Neural and Drug-induced Inhibition in the Cerebral Cortex. Nature 216, 922–923 (1967). https://doi.org/10.1038/216922a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/216922a0
This article is cited by
-
Cholinergic neurons and fibres in the rat visual cortex
Journal of Neurocytology (1986)
-
Effect of direct and transcallosal stimulation on inhibition of unit activity in the cat association cortex
Neurophysiology (1981)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
