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Tumours induced by Chicken Sarcoma in Monkeys conditioned with Progesterone

Abstract

REPORTS of skin and organ transplantation, as well as of tumour induction and serial passage in laboratory animals, have casually mentioned that the duration of graft survival is enhanced by pregnancy1–3; more tumours can be induced in pregnant and adult female than in adult male rodents3. There are examples of experimental animals, unexpectedly found to be pregnant, which have been discarded from the experiment4 with this explanation. Furthermore, several workers have shown newborn mammals to be more susceptible to virus infection, and less resistant to skin or organ transplantation, than mature animals of the same species.

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References

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  2. Medawar, P. B., and Sparrow, E. M., J. Endocrinol., 14, 240 (1956).

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  3. Haines, R. F., Johnson, A. G., and Peteoing, H. G., Fed. Proc., 26, 934 (1967).

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MUNROE, J., WINDLE, W. Tumours induced by Chicken Sarcoma in Monkeys conditioned with Progesterone. Nature 216, 811–813 (1967). https://doi.org/10.1038/216811a0

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  • DOI: https://doi.org/10.1038/216811a0

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