Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Establishment of Cell Lines from Peripheral Leucocytes in Infectious Mononucleosis

Abstract

CELL lines have been established in vitro from peripheral leucocytes taken from patients with leukaemia1–4, lymphomas1 and malignant melanoma with leukaemoid reaction5. There are also two reports of cell lines derived from presumably normal leucocytes6,7. We have found that in infectious mononucleosis cell lines can readily be established from peripheral leucocytes.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Moore, G. E., Grace, J. T., Citron, P., Gerner, R., and Burns, A., NY St. J. Med., 66, 2757 (1966).

    CAS  Google Scholar 

  2. Armstrong, D., Proc. Soc. Exp. Biol. and Med., 122, 475 (1966).

    Article  CAS  Google Scholar 

  3. Lucas, L. S., Whang, J. J. K., Tjio, J. H., Manaker, R. A., and Zeve, V. H., J. Nat. Cancer Inst., 37, 753 (1966).

    CAS  PubMed  Google Scholar 

  4. Foley, G. E., Lazarus, H., Farber, S., Uzman, B. G., Boone, B. A., and McCarthy, R. E., Cancer, 18, 522 (1965).

    Article  CAS  Google Scholar 

  5. Moore, G. E., and Pickren, J. W., Lab. Invest., 16, 882 (1967).

    CAS  PubMed  Google Scholar 

  6. Moore, G. E., Gerner, R. E., and Franklin, H. A., J. Amer. Med. Assoc., 199, 519 (1967).

    Article  CAS  Google Scholar 

  7. Gerber, P., and Birch, S. M., Proc. US Nat. Acad. Sci., 58, 478 (1967).

    Article  ADS  CAS  Google Scholar 

  8. Robinson, L., and Smith, H., J. Clin. Pathol., 19, 339 (1966).

    Article  CAS  Google Scholar 

  9. Pope, J. H., Achong, B. G., Epstein, M. A., and Biddulph, J., J. Nat. Cancer Inst., 39 (in the press, 1967).

  10. Epstein, M. A., and Barr, Y. M., J. Nat. Cancer Inst., 34, 231 (1965).

    Article  CAS  Google Scholar 

  11. Besser, G. M., Davis, J., Duncan, C., Kirk, B., and Kuper, S. W. A., Brit. J. Haematol., 13, 189 (1967).

    Article  CAS  Google Scholar 

  12. Benyesh-Melnick, M., in Viruses Inducing Cancer, Implications for Therapy (edit. by Burdette, W. J.), 305 (University of Utah Press, 1966).

    Google Scholar 

  13. Dameshek, W., and Gunz, F., in Leukemia, 404 (Grune and Stratton. New York, 1964).

    Google Scholar 

  14. Dameshek, W., Lancet, i, 333 (1967).

  15. Zeve, V. H., Lucas, L. S., and Manaker, R. A., J. Nat. Cancer Inst., 37, 761 (1966).

    CAS  PubMed  Google Scholar 

  16. Epstein, M. A., Achong, B. G., and Barr, Y. M., Lancet, i, 702 (1964).

  17. Stewart, S. E., Lovelace, R., Whang, J. J., and Ngu, V. A., J. Nat. Cancer Inst., 34, 319 (1965).

    Article  CAS  Google Scholar 

  18. Rabson, A. S., O'Conor, G. T., Baron, S., Whang, J. J., and Legallais, F. Y., Intern. J. Cancer, 1, 89 (1966).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

POPE, J. Establishment of Cell Lines from Peripheral Leucocytes in Infectious Mononucleosis. Nature 216, 810–811 (1967). https://doi.org/10.1038/216810a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/216810a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing