Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Effect of Gastric Juice and pH on Inorganic Iron in Solution

Abstract

THE absorption of ionized iron in humans is influenced by gastric acidity1–3. Ferric ions in solution usually form complex mixtures in which the metal is co-ordinated to a number of hydroxyl ions and in some conditions there is a high degree of polymerization4. Ferrous ions do not undergo such marked changes but tend to be oxidized to ferric forms when the pH approaches neutrality4. Filtration on ‘Sephadex’ gel has been used in this laboratory to examine the behaviour of iron salts at different pHs and after mixing with gastric juice.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Jacobs, P., Bothwell, T., and Charlton, R. W., J. Appl. Physiol., 19, 187 (1966).

    Article  Google Scholar 

  2. Jacobs, A., Rhodes, J., and Peters, D. K., Campbell, H., and Eakins, J. D., Brit. J. Haematol., 12, 728 (1966).

    Article  CAS  Google Scholar 

  3. Jacobs, A., Rhodes, J., and Eakins, J. D., Scand. J. Haematol., 4, 105 (1967).

    Article  CAS  Google Scholar 

  4. Cotton, F. A., and Wilkinson, G., Advanced Inorganic Chemistry, second ed. (John Wylie, 1966).

    Google Scholar 

  5. Young, D. S., and Hicks, H. M., J. Clin. Pathol., 18, 98 (1965).

    Article  CAS  Google Scholar 

  6. Rhodes, J., Goodall, P., and Apsimon, H. T., Gut, 7, 515 (1966).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

JACOBS, A. Effect of Gastric Juice and pH on Inorganic Iron in Solution. Nature 216, 707–708 (1967). https://doi.org/10.1038/216707a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/216707a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing