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Effects of Presynaptic and Postsynaptic Inhibition on the Variability of the Monosynaptic Reflex

Nature volume 216, pages 292–293 (1967)Cite this article

Abstract

SUCCESSIVE monosynaptic reflexes evoked by essentially constant afferent volleys usually show considerable fluctuations in size1,2. It has been suggested1–3 that the chief cause of such variability would be background activity of interneurones impinging on to motoneurones. Monosynaptic transmission from afferent fibres to motoneurones may be controlled at the postsynaptic as well as the presynaptic level4, and so the question arises: which internuncial system, terminating either pre- or postsynaptically, is actually contributing to the monosynaptic reflex fluctuations ? For this reason we have compared the effects of afferent volleys leading to pre-and postsynaptic inhibition on fluctuations of the monosynaptic reflex.

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References

  1. Hunt, C. C., J. Gen. Physiol., 38, 801 (1955).

    Article  CAS  Google Scholar 

  2. Somjen, G. G., and Heath, J. C., Exp. Neurol., 15, 79 (1966).

    Article  CAS  Google Scholar 

  3. Rall, W., and Hunt, C. C., J. Gen. Physiol., 39, 397 (1956).

    Article  CAS  Google Scholar 

  4. Eccles, J. C., The Physiology of Synapses (Springer–Verlag, Berlin, 1964).

    Book  Google Scholar 

  5. Otterman, J., IRE Trans., AC5, 11 (1960).

    Google Scholar 

  6. Eccles, J. C., Eccles, R. M., and Lundberg, A., J. Physiol., 138, 227 (1957).

    Article  CAS  Google Scholar 

  7. Eccles, J. C., Fatt, P., and Koketsu, K., J. Physiol., 126, 524 (1954).

    Article  CAS  Google Scholar 

  8. Kuno, M., J. Physiol., 175, 100 (1964).

    Article  CAS  Google Scholar 

  9. Wall, P. D., in Physiology of Spinal Neurons (edit. by Eccles, J. C., and Shade, J. P.), 22 (Elsevier, 1964).

    Google Scholar 

  10. Lund, S., Lundberg, A., and Vyklicky, L., Acta Physiol. Scand., 64, 345 (1965).

    Article  CAS  Google Scholar 

  11. Green, D. G., and Kellerth, J. O., Science, 52, 1097 (1966).

    Article  ADS  Google Scholar 

Download references

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Authors and Affiliations

  1. Departments of Physiology and Electrical Engineering, Centro de Investigación y de Estudios Avanzados del Instituto Politecnico Nacional, Mexico

    P. RUDOMIN & H. DUTTON

Authors
  1. P. RUDOMIN
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  2. H. DUTTON
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RUDOMIN, P., DUTTON, H. Effects of Presynaptic and Postsynaptic Inhibition on the Variability of the Monosynaptic Reflex. Nature 216, 292–293 (1967). https://doi.org/10.1038/216292a0

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