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Electrophoretic Separation of the Soluble Proteins of Brucei Sub-group Trypanosomes

Abstract

THE brucei sub-group trypanosomes, now assigned to the sub-genus Trypanozoon by Hoare1, have antigens which continually undergo variation and which are apparently soluble proteins localized in the cytoplasm2,3. The nature of the variation is not yet clear and the antigens have not been well characterized, probably because of the lack of a satisfactory method of separation. Chang et al.4 have drawn attention to the advantage to physiology and genetics of efficient separation of protein fractions, and the immunology of trypanosomes would also benefit by such a method, especially with regard to the correlation of their antigenic and enzyme properties.

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NJOGU, A., HUMPHRYES, K. Electrophoretic Separation of the Soluble Proteins of Brucei Sub-group Trypanosomes. Nature 216, 280–282 (1967). https://doi.org/10.1038/216280a0

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