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Effect of Laparotomy on Plasma Renin Activity in the Rabbit

Nature volume 215, pages 542–543 (1967)Cite this article

Abstract

WHILE trying to find an effective stimulus for the release of renin in the rabbit, we inserted a catheter into the left lumbo-adrenal artery and pushed the tip into the left renal artery close to the kidney. With no further manipulation the plasma renin activity increased within a few hours and subsequently fell to normal or less than normal values during the next few days. This unexpected observation encouraged us to investigate the changes in plasma renin brought about by opening the abdomen.

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Authors and Affiliations

  1. Department of the Regius Professor of Medicine, University of Oxford, Radcliffe Infirmary, Oxford

    J. K. MCKENZIE, J. W. RYAN & M. R. LEE

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  1. J. K. MCKENZIE
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  2. J. W. RYAN
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  3. M. R. LEE
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MCKENZIE, J., RYAN, J. & LEE, M. Effect of Laparotomy on Plasma Renin Activity in the Rabbit. Nature 215, 542–543 (1967). https://doi.org/10.1038/215542b0

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