Abstract
IT has been shown that the acute in vitro effects of adrenal hormones on the rate of uptake of glucose by diaphragms of chronically morphinized rats differ markedly from the normal effects1–3, and the evidence suggests that the changes induced by morphine which affect hormone sensitivity involve a modification of membrane properties4. The possibility that such changes depend, at least in part, on an ability of morphine specifically to interfere with the formation and function of metal ion complexes within membranes encouraged us to investigate the effects of varying magnesium concentrations in the incubating medium used in our experiments.
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WALSH, E., POON, M. Morphine cancels Effect of Magnesium on Hormone-sensitive Uptake of Glucose by Muscle. Nature 215, 525–526 (1967). https://doi.org/10.1038/215525a0
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DOI: https://doi.org/10.1038/215525a0
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