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Correlation between Kinetically Defined Calcium Compartments and Contractile Response in Rabbit Atrium

Nature volume 215, pages 1182–1183 (1967)Cite this article

Abstract

THE importance of calcium ions in the contraction mechanism of skeletal and cardiac muscle has been established on the basis of previous work1–15. Calcium seems to be stored in the sarcoplasmic reticulum and plays a critical part in coupling excitation with contraction when released into the sarcoplasm of these tissues after depolarization of the membrane. The exact way in which calcium performs this function is not clear, and, furthermore, calcium in cardiac tissue is divided into at least two components by kinetic studies with calcium-45 (refs. 16–19). This communication presents evidence for the applicability of kinetic analysis to the contraction process in cardiac tissue.

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Author notes

  1. THOMAS F. DECARO

    Present address: Biology Department, PMC Colleges, Chester, Pennsylvania

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  1. Department of Physiology, University of Pennsylvania Medical School, Philadelphia

    THOMAS F. DECARO

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  1. THOMAS F. DECARO
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DECARO, T. Correlation between Kinetically Defined Calcium Compartments and Contractile Response in Rabbit Atrium. Nature 215, 1182–1183 (1967). https://doi.org/10.1038/2151182a0

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