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Effect of Endotoxin on Resistance in the Early Period of Ontogenesis

Nature volume 214, pages 699–700 (1967)Cite this article

A Corrigendum to this article was published on 17 June 1967

Abstract

ORGANISMS react to bacterial antigens in the early stages of ontogenesis, and it has been reported that bacterial antigens raise the resistance of the embryo1–3, while the antigenic stimulation of the embryo4 and the subsequent second vaccination of newly hatched chicks considerably enhance the resistance of the chicks in their first few weeks of life5. Our previous studies have shown that it is best to perform the first stimulation on the twelfth day of incubation, and the second vaccination on the first day after hatching6.

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References

  1. Karthigasu, K., and Jenkin, C. R., Immunology, 6, 255 (1963).

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  2. Finkelstein, R. A., and Ransom, J. P., J. Exp. Med., 118, 314 (1963).

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  4. Grosgrove, A. S., and Morris, R. C., English Patent A 1 M (A 61 d), No. 987842 (1965).

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  6. Pavel, Ü., and Peterson, K., Eksperimentalna Medicina i Morfologija (Sophia), 4, 214 (1965) (in Bulgarian).

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  7. Pavel, Ü., and Peterson, K., Eesti Pollumajunduse Akad. Teaduslike Tööde Kogumik, 38, 87 (1964) (in Russian).

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Authors and Affiliations

  1. Department of Microbiology, Estonian Academy of Agriculture, Tartu, Estonian S.S.R., U.S.S.R.

    K. PETERSON & Ü. PAVEL

  2. Department of Genetics and Darwinism, Tartu State University, Tartu, Estonian S.S.R., U.S.S.R.

    K. PETERSON & Ü. PAVEL

Authors
  1. K. PETERSON
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  2. Ü. PAVEL
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PETERSON, K., PAVEL, Ü. Effect of Endotoxin on Resistance in the Early Period of Ontogenesis. Nature 214, 699–700 (1967). https://doi.org/10.1038/214699a0

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