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A “New” Allotypic Specificity (A9) of Rabbit Immunoglobulin

Abstract

THIS communication describes a hitherto unknown allotypic specificity of rabbit immunoglobulin molecules. The designation of “A9” is proposed for this specificity. The designations A1–A6 were previously assigned1 to the first six well established specificities2–7. The designations A7 and A8 have since been given to two other specificities7–9. The “new” specificity, A9, was found to be carried mainly by the IgG molecules and determined by a gene, allelic to other (A4, A5 and A6) genes, belonging to the b allotypic locus. This close genetic association with other Ab specificities makes it very likely that A9, like A4, A5 and A6, is also localized on the L-chain of the immunoglobulin molecule.

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DUBISKI, S., MULLER, P. A “New” Allotypic Specificity (A9) of Rabbit Immunoglobulin. Nature 214, 696–697 (1967). https://doi.org/10.1038/214696a0

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