Abstract
DURING an investigation of the fluorescence properties of biological substances in gelatine models it was found that after treatment with formaldehyde reserpine showed fluorescence characteristics similar to those of 5-hydroxytryptamine (unpublished results of Schofield, Ho and Southwell). It was suggested that in vivo cellular localization of reserpine by autoradiography would be of interest in the investigation of the effect of this drug on the content of 5-hydroxytryptamine in various tissues. This communication is a preliminary report on observations of the cellular localization of reserpine in the brain.
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HO, A. Localization of Tritiated Reserpine in the Area Postrema and the Floor of the Fourth Ventricle of the Mouse. Nature 214, 1266–1267 (1967). https://doi.org/10.1038/2141266a0
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DOI: https://doi.org/10.1038/2141266a0
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