Abstract
IT is well known that the amphibian melanophores can react in vitro to certain stimuli either by contraction or by dispersal. The most studied of these reactions are those due to melanophore-stimulating hormone, melatonin and xanthines. This communication shows that this reaction of amphibian melanophores can also be achieved by a hitherto unsuspected stimulus. It reports for the first time the sensitization of frog skin melanophores by a mammalian antibody, as a result of which melanophore dispersal can be demonstrated on contact with specific antigen.
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References
Hogben, L., and Slome, D., Proc. Roy. Soc. B., 108, 10 (1931).
Broklehurst, W. E., Humphrey, J. H., and Perry, W. L. M., Immunology, 4, 67 (1961).
Nielson, C. B., Terres, G., and Feigen, G. A., Science, 130, 41 (1959).
Halpern, B. N., Liaconpoulos, P., Liacopoulos-Brit, M., Binaghi, R., and Vanneer, F., Immunology, 2, 351 (1959).
Feigen, G. A., Nielsen, C. B., and Terres, G., J. Immunol., 89, 717 (1962).
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ABDULLA, Y., GUPTA, T. Sensitization of Frog Melanophores by Mammalian Antibody. Nature 214, 1231–1232 (1967). https://doi.org/10.1038/2141231a0
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DOI: https://doi.org/10.1038/2141231a0
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