Abstract
HELLSTRÖM et al.1 showed that homogenates of allogeneic spleens caused a greater decrease in the number of tumour cells in tissue culture than did homogenates of syngeneic spleens. They called this phenomenon “syngeneic preference”2,3 in tissue culture. The action of phytohaemagglutinin on target cells plus allogeneic lymphocytes is also caused by “syngeneic preference”4. The extent to which this phenomenon is applicable to other tissue systems is unknown.
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References
Hellström, K. E., Hellström, J., and Haughton, G., Nature, 204, 661 (1964).
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Svet-Moldavsky, G. J., and Chernyakhovskaya, J. Yu., Nature, 204, 799 (1964).
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CHERNYAKHOVSKAYA, I., KADAGGIDZE, Z. & SVET-MOLDAVSKY, G. Effect of Syngeneic and Allogeneic Lymphocytes on L-cells and Mouse Embryo Fibroblasts in vitro. Nature 214, 1229–1230 (1967). https://doi.org/10.1038/2141229a0
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DOI: https://doi.org/10.1038/2141229a0
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