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Urinary Phenols in Melanoma

Nature volume 213, pages 520–521 (1967)Cite this article

Abstract

RECENT observations1 on the urinary metabolites of 3 : 4-dihydroxyphenylalanine (DOPA) have prompted us to examine the excretion of phenolic acids in five patients with malignant melanoma, three of whom had hepatic metastases and melanuria and two only locally recurrent cutaneous and lymphatic lesions; all were on uncontrolled diets. Phenolic acids were examined chromatographically2 in both hydrolysed and unhydrolysed urines in all cases.

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Author information

Authors and Affiliations

  1. Royal Air Force Institute of Aviation Medicine, Farnborough, Hampshire

    R. F. COWARD & P. SMITH

  2. Department of Chemical Pathology, Group Pathology Laboratory, General Hospital, Southampton

    J. E. MIDDLETON

Authors
  1. R. F. COWARD
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  2. P. SMITH
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  3. J. E. MIDDLETON
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COWARD, R., SMITH, P. & MIDDLETON, J. Urinary Phenols in Melanoma. Nature 213, 520–521 (1967). https://doi.org/10.1038/213520a0

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