Abstract
ANY marked increase in the metabolic demands of the cerebral cortex, caused, for example, by increased activity, is accompanied by an intensification of cortical circulation1–3. This occurs independently of the systemic arterial pressure which remains unaltered. The width of the major arteries of the brain (internal carotids and vertebrals) does not change in conditions of increased cortical activity4 and even diminishes after a temporary deficiency of blood supply to the brain5,6. These arteries therefore do not, in the above conditions, contribute to an increase in cerebral circulation. It was therefore necessary to learn more about the functional behaviour of both pial and cortical arteries, as the possible vascular mechanisms responsible for increase of blood supply to the cerebral cortex when its metabolic demands are heightened.
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MCHEDLISHVILI, G., BARAMIDZE, D. & NIKOLAISHVILI, L. Functional Behaviour of Pial and Cortical Arteries in Conditions of Increased Metabolic Demand from the Cerebral Cortex. Nature 213, 506–507 (1967). https://doi.org/10.1038/213506a0
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DOI: https://doi.org/10.1038/213506a0
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