Abstract
RNA extracted from the spleens of mice immunized with sheep red blood cells converts some spleen cells from non-immunized mice to form antibody. The substance responsible for this conversion is RNA rich material with a coefficient of sedimentation between 8S and 12S. There may be specific recognition sites for this RNA on a few competent recipient cells which respond by producing antibody.
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COHEN, E. Conversion of Non-immune Cells into Antibody-forming Cells by RNA. Nature 213, 462–465 (1967). https://doi.org/10.1038/213462a0
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DOI: https://doi.org/10.1038/213462a0
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