Abstract
INVESTIGATIONS of mammalian haemoglobins have given much biological information1–3, but although notable advances, particularly in human haemoglobins, have been made, many aspects of the subject remain obscure or hypothetical. The genetics of haemoglobin is particularly in need of clarification. Valuable genetic information has been acquired from the use of model hybrid systems4,5, and the findings complement information laboriously obtained from investigation of occasionally suitable human families. We have investigated the pattern of inheritance of haemoglobins in the Equidae and their interspecific hybrids, in which the karyotypes of the individual species have been well defined6, by electrophoresis, pep tide mapping, and separation of globin sub-units.
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References
Gratzer, W. B., and Allison, A. C., Biol. Rev. Cambridge Phil. Soc., 35, 459 (1960).
Rucknagel, D. L., and Neel, J. V., Prog. Med. Genet., 1, 158 (1961).
Schroeder, W. A., Ann. Rev. Biochem., 32, 301 (1963).
Young, W. J., Porter, J. E., and Childs, B., Science, 143, 140 (1964).
Trujillo, J. M., Walden, B., O'Neill, P., and Anstall, H. B., Science., 148, 1603 (1965).
Trujillo, J. M., Stenius, C., Christian, L., Ohno, S., Chromosoma, 13, 243 (1962).
Ingram, V. M., Biochim. Biophys. Acta, 28, 539 (1958).
Kirkman, H. N., and Hendrickson, E. M., Amer. J. Human Genet., 15, 241 (1963).
Kostka, V., and Carpenter, F. H., J. Biol. Chem., 239, 1799 (1964).
Shows, jun., T. B., Tashian, R. E., Brewer, G. J., and Dern, R. J., Science, 145, 1056 (1964).
Chernoff, A. I., and Pettit, N. M., Blood, 24, 750 (1964).
Fine, J. M., and Waszczenko, E., Nature, 181, 269 (1958)
Bangham, A. D., and Lehmann, H., Nature, 181, 268 (1958).
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TRUJILLO, J., WALDEN, B., O'NEILL, P. et al. Inheritance and Sub-unit Composition of Haemoglobin in the Horse, Donkey and their Hybrids. Nature 213, 88–90 (1967). https://doi.org/10.1038/213088b0
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DOI: https://doi.org/10.1038/213088b0
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