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Effect of Growth Hormone on Tubular Reabsorption of Glucose and Phosphate

Nature volume 213, pages 85–86 (1967)Cite this article

Abstract

IT is now well established that growth hormone has some renotropic properties. Besides its enhancing effect on renal plasma flow and glomerular filtration rate (GFR) in dog1,2 and man3–5, growth hormone has been shown to raise tubular reabsorption of phosphate in man3–5 and in normal and parathyroidectomized dogs6. In some respects, the mechanism of tubular transport of glucose is similar to that of phosphate; some common metabolic pathways are probably involved in their tubular transport since glucose has been shown to compete with phosphate for reabsorption7. It was therefore of interest to investigate the effect of growth hormone on tubular transport of glucose. For this purpose maximal tubular reabsorption of glucose (TmG) was measured before and after administration of bovine growth hormone (BGH) in the dog.

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Authors and Affiliations

  1. Université Libre de Bruxelles Clinique Médicale, Hôpital Universitaire Brugmann, 4, Place Van Gehuchten

    M. ABRAMOW & J. CORVILAIN

  2. Laboratoire de Médecine Experiméntale, Fondation Reine Elisabeth, 1, Avenue Jean Crocq

    M. ABRAMOW & J. CORVILAIN

Authors
  1. M. ABRAMOW
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  2. J. CORVILAIN
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ABRAMOW, M., CORVILAIN, J. Effect of Growth Hormone on Tubular Reabsorption of Glucose and Phosphate. Nature 213, 85–86 (1967). https://doi.org/10.1038/213085a0

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