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A Method for determining the Total and Differential Count of Langerhans's Cells in the Skin

Abstract

LANGERHANS'S cells from the digest of the black epidermis of the guinea-pig have been classified according to the number of processes in the cells1,2. Cells possessing five, four, three and two dendritic processes are classified as types I, II, III and IV, respectively. This communication describes a method of counting the absolute total, the differential number and percentage differential number of these cells.

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SHUKLA, R. A Method for determining the Total and Differential Count of Langerhans's Cells in the Skin. Nature 212, 955–956 (1966). https://doi.org/10.1038/212955a0

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