Abstract
CHRISTIANSEN1 has objected to the “half-chair” conformation (C2 symmetry) of cyclohexane as the transition form for inversion of the chair conformation (presumably through the twisted boat) as proposed by one of us2. Earlier calculations3 had already indicated that the route through the boat (or twist-boat) form would permit inversion of the chair form of cyclohexane with lower activation energy than that of the planar hexagon.
Similar content being viewed by others
Article PDF
References
Christiansen, J. A., Nature, 211, 184 (1966).
Hendrickson, J. B., J. Amer. Chem. Soc., 83, 4537 (1961).
Beckett, C. W., Pitzer, K. S., and Spitzer, R., J. Amer. Chem. Soc., 69, 2488 (1957).
Jensen, F. R., Noyce, D. S., Sederholm, C. H., and Berlin, A. J., J. Amer. Chem. Soc., 84, 386 (1962).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HENDRICKSON, J., PITZER, K. Transition State in the Inversion of Cyclohexane. Nature 212, 749 (1966). https://doi.org/10.1038/212749a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/212749a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.