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Inducible D-Malic Enzyme in Escherichia coli

Abstract

D-MALIC acid is usually referred to as the unnatural form of malic acid and is considered to be metabolically inert. We find that extracts of E. coli cells which have been grown on, or in the presence of, D-malate contain an inducible D-malic enzyme which catalyses the reversible reaction (1), as well as a constitutive, partly inducible, L-malic enzyme (EC 1.1.1.40 L-malate: TPN oxidoreductase, decarboxy-lating) which catalyses reaction (2).

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References

  1. Veiga Salles, J. B., and Ochoa, S., J. Biol. Chem., 187, 849 (1950).

    CAS  PubMed  Google Scholar 

  2. Burns, R. O., Umbarger, H. E., and Gross, S. R., Biochemistry, 2, 1053 (1963).

    Article  CAS  Google Scholar 

  3. Magee, P. T., and Snell, E. E., Biochemistry, 5, 409 (1965).

    Article  Google Scholar 

  4. Korkes, S., del Campillo, A., and Ochoa, S., J. Biol. Chem., 197, 891 (1950).

    Google Scholar 

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STERN, J., HEGRE, C. Inducible D-Malic Enzyme in Escherichia coli. Nature 212, 1611–1612 (1966). https://doi.org/10.1038/2121611a0

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