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Changes in the ATP Content of the Calf Thymus Nuclei under the Influence of Insulin

Abstract

THE relative autonomy of cell nuclei established in recent years is determined to a certain extent by the poor permeability of the membrane to certain cell metabolites9. The nuclei possess substrates sufficient for biological oxidation2,9 and they can decompose the exogenic glucose in metabolic reactions providing the ATP necessary for the synthesis of the macromolecules in them. Nuclei incubated in a glucose medium have reduced oxygen consumption, but use more ATP compared with the nuclei incubated in the absence of substrate9.

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DANCHEVA, K. Changes in the ATP Content of the Calf Thymus Nuclei under the Influence of Insulin. Nature 212, 1361–1362 (1966). https://doi.org/10.1038/2121361a0

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