Abstract
EXPERIMENTAL results reported in previous papers have suggested that rat brain liberates 5-hydroxytryptamine (5-HT) after X-irradiation1,2. The biochemical and physiological investigation of irradiated experimental animals is complicated by non-specific neuroendocrine reactions which play a part in the adaptation syndrome. In order to exclude this factor, we carried out experiments on adrenalectomized rats, which are also more sensitive to X-irradiation. The main changes in the content of 5-hydroxyindoles after X-irradiation were observed in the brain stem1, which contains the centres which regulate and co-ordinate the endocrine system.
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PALAIĆ, D., SUPEK, Z. Liberation of 5-Hydroxytryptamine in the Brain Stem of Adrenalectomized Rats after X-irradiation. Nature 210, 970–971 (1966). https://doi.org/10.1038/210970a0
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DOI: https://doi.org/10.1038/210970a0
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