Abstract
WITH the recent development of potent penicillinase-resistant semi-synthetic cephalosporins1, there is considerable interest in the parent antibiotic, cephalosporin C (ref. 2). This antibiotic, which displays a peak of ultra-violet absorption at 260 mµ, is often detected on paper chromatograms by exposure to a source of ultraviolet light. Using this technique during somo investigations on the biosynthesis of the antibiotic3, I noted an extreme lability of cephalosporin C to ultra-violet light.
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DEMAIN, A. Destruction of Cephalosporin C by Ultraviolet Light. Nature 210, 426–427 (1966). https://doi.org/10.1038/210426b0
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DOI: https://doi.org/10.1038/210426b0
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