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Inactivation of T-2 Bacteriophage by Sensitized Leucocytes in vitro

Abstract

ALTHOUGH in vitro investigations of the primary1 and secondary2,3 phases of the immune response have been reported, few investigators have used blood as a source of immunologically competent cells4–6. The use of blood instead of lymphoid organs as a source of cells enables the investigator to obtain multiple samples of a homogeneous cell population. This communication reports a preliminary approach to an immunological investigative system consisting of sensitized rabbit blood leucocytes and T-2 bacteriophage, a particulate antigen that can be assayed by a procedure which is relatively simple, sensitive and quantitative.

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YOUNG, R., RUDDLE, F. Inactivation of T-2 Bacteriophage by Sensitized Leucocytes in vitro. Nature 208, 1105–1106 (1965). https://doi.org/10.1038/2081105a0

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