Metabolic Activity of Monolayer Tissue Cultures of Human Thyroid

Abstract

STUDIES of iodine metabolism by dispersed human thyroid cells have been reported by Pulvertaft et al.¹. Pastan² and Tong et al.³ have reported similar studies on calf and sheep thyroid cells, respectively. The latter authors' findings suggest that the follicular structure of intact thyroid tissue is not indispensable for the formation of thyroid hormones. Kerkof et al.⁴ have reported their interesting observation of the re-organization of the monolayers of thyroid cells in tissue culture into a structural pattern resembling cross-sections of intact thyroid tissue when thyroid stimulating hormone was included in the medium.