Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Isolation and Characterization of an Actinophage (Phage A) active against a Strain of Streptomyces producing Novobiocin

Abstract

AN actinophage (phage A), active against Streptomyces C1V23 obtained from strain S-8001,2, a producer of novobiocin, has been isolated from industrial fermentation broth cultures with scanty or abnormal mycelial growth and no antibiotic production. So far as we know, this is the first time that an actinophage destructive to a Streptomyces strain producing novobiocin has been isolated.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Rolland, G., Sensi, P., De Ferrari, G. A., Maffii, G., Timbal, M. T., Silvestri, L. G., Il Farmaco (Sci. ed.), 1, 549 (1956).

    Google Scholar 

  2. Rolland, G., Sensi, P., Maffii, G., Timbal, M. T., and Silvestri, L. G., IX Congresso Nazionale di Microbiologia—Palermo (1956).

    Google Scholar 

  3. Gratia, A., Ann. Inst. Pasteur, 57, 652 (1936).

    Google Scholar 

  4. St. Clair, J., and McCoy, E., J. Bacteriol., 77, 131 (1959).

    PubMed Central  Google Scholar 

  5. Thiemann, J. E., Hengeller, C., and Virgilio, A., Nature, 193, 1104 (1962).

    Article  ADS  CAS  Google Scholar 

  6. Van Alstyne, M. H., Otto, R. H., and McCoy, E., J. Bacteriol., 70, 113 (1955).

    CAS  PubMed  Google Scholar 

  7. Weindling, R., Tresner, H. D., and Backus, E. J., Nature, 189, 603 (1961).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

HENGELLER, C., LICCIARDELLO, G., TUDINO, V. et al. Isolation and Characterization of an Actinophage (Phage A) active against a Strain of Streptomyces producing Novobiocin. Nature 205, 418–419 (1965). https://doi.org/10.1038/205418a0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/205418a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing